Biomolecular Simulation
Ajit Kumar
Manish Kesherwani
Slow conformational changes in Transporter channel and membrane associated protein observing molecular events is difficult in all atom simulation becoz of massively time expenses in calculating conformations.So Macromolecular Simulation should be used in used different way for calculation of conformattion one more prominent method used is coarsed grained dynamics this is statistical ensemble based molecular event characterisation. Recently Cafemol software by kyoyo univ japan has developed best in giving prominet results. Carma is good software for PCA analysis for conformational clustering.